There were times, particularly during the conclusion of the debate, when almost every comment from Trump was inaccurate. Most of his false claims were ones he's made before and which have been repeatedly fact-checked and found to be false, rather than one-time slips or gaffes.
Fox News's Chris Wallace moderated the debate, which covered both candidates' records as well as the Supreme Court vacancy, Covid-19, the economy, the recent racial justice protests across the country and questions about the integrity of the upcoming election.
Here's what they said.
Trump claimed that Biden's son Hunter Biden got a $3.5 million payment from the wife of the former mayor of Moscow. "Why is it, just out of curiosity, the mayor of Moscow's wife gave your son $3.5 million?" Trump said.
Facts First: This needs context. Hunter Biden denies the allegation. His lawyer, George Mesires, told CNN that Hunter Biden was not an owner of the firm Senate Republicans allege received the $3.5 million payment in 2014.
"Hunter Biden had no interest in and was not a 'co-founder' of Rosemont Seneca Thornton, so the claim that he was paid $3.5 million is false," Mesires said.
Hunter Biden was a co-founder and CEO of the investment firm Rosemont Seneca Advisors. But Mesires said Hunter Biden did not co-found Rosemont Seneca Thornton. It's not clear what connection exists between Rosemont Seneca Advisors and Rosemont Seneca Thornton.
Neither the Senate report nor Trump have provided any evidence that the payment was corrupt or that Hunter Biden committed any wrongdoing.
-- Daniel Dale and Jeremy Herb
Coronavirus and the economy
Trump claimed several times that Biden wants to shut down the country to address the coronavirus.
"He wants to shut down this country and I want to keep it open," Trump said.
It's also worth noting that presidents themselves cannot shut down the country. The pandemic restrictions governing people's movements and the operations of businesses and other entities have been imposed by state and local officials, not Trump.
-- Tara Subramaniam
Coronavirus travel restrictions
Defending his response to the coronavirus pandemic, Trump referenced the travel restrictions his administration imposed on foreign nationals who had been in China, then attacked Biden for remarks he had made the same day.
Addressing his opponent, Trump said, "I closed it, and you said, 'He's xenophobic. He's a racist and he's xenophobic,' because you didn't think I should have closed our country."
Facts First: This needs context. It's not clear Biden even knew about Trump's China travel restrictions when he called Trump xenophobic on the day the restrictions were unveiled; Biden has never explicitly linked his accusation of xenophobia to these travel restrictions.
The campaign says Biden's January 31 accusations -- that Trump has a record of "hysterical xenophobia" and "fear mongering" -- were not about the travel restrictions at all. The campaign says Biden did not know about the restrictions at the time of his speech, since his campaign event in Iowa started shortly after the Trump administration briefing where the restrictions were revealed by Health and Human Services Secretary Alex Azar.
Given the timing of the Biden remarks, it's not unreasonable for Trump to infer that the former vice president was talking about the travel restrictions. But Biden never took an explicit position on the restrictions until his April declaration of support.
-- Tara Subramaniam
Veterans' health care
During a discussion on health care and insurance, Trump claimed 308,000 "military people" died because Biden "couldn't provide them proper health care."
Facts First: This claim is misleading and misconstrues the findings of a government report.
But the report did not reach conclusions about whether lack of health care caused those deaths, and due to data limitations, the VA's inspector general's office could not determine how many of those records actually represented veterans who applied for health care benefits.
Moreover, the database in question contained some records for veterans who died before 1998, when Biden was a senator. And the report projected that at least 477,000 records pending in the system were missing application dates, which made the system "unreliable" for understanding the timeliness of care.
-- Curt Devine
Affordable Care Act
Biden turned a question about the Supreme Court into a defense of the Affordable Care Act, which was enacted while he was in office.
"He's in the Supreme Court right now, trying to get rid of the Affordable Care Act, which will strip 20 million people from having insurance," Biden said of Trump's support of a case coming up before the justices that could overturn the landmark health reform law.
Facts First: Health care experts say this figure is roughly accurate. It is an estimate from the Obama administration as to how many people gained coverage under the Affordable Care Act.
Some 12 million newly eligible, low-income adults have obtained coverage under Obamacare's Medicaid expansion provision, according to the Kaiser Family Foundation. Some 38 states and the District of Columbia have broadened their coverage or passed ballot measures to do so.
And roughly 10.7 million were enrolled in individual coverage on the Affordable Care Act exchanges in February, according to the Centers for Medicare and Medicaid Services.
-- Tami Luhby
US trade deficit
Biden suggested that the United States currently has a higher trade deficit with both China and Mexico than it has had before.
"His trade deals are the same way, he talks about these great trade deals," Biden said. "You know, he talks about the art of the deal. China's made -- perfected the art of the steal. We have a higher deficit with China now than we did before. We have the highest deficit, trade deficit with Mexico."
Facts First: Biden was wrong on China, but correct on Mexico.
He would have been right on China in 2018, when the goods and services trade deficit with China hit $380 billion, but it's no longer true, according to data from the Bureau of Economic Analysis. The gap fell to $308 billion in 2019 -- which is the lowest it's been since 2013.
The US goods and services trade deficit with Mexico grew to a record $104 billion in 2019. It was $64 billion in 2016, before Trump took office.
-- Katie Lobosco
Jobs and the economy
Biden claimed that Trump is "going to be the first President of the United States to leave office having fewer jobs in his administration than when he became President."
Facts first: This is correct looking at the last 67 years, but the government data doesn't go back far enough to compare all presidents' jobs performance in history.
That said, the dramatic job losses during Trump's term came during the pandemic shutdown, when more than 22 million jobs vanished.
The official jobs numbers that the Bureau of Labor Statistics puts out go back to 1939, the middle of Franklin D. Roosevelt's administration.
-- Anneken Tappe
In attacking Biden for his advocacy of the 1994 crime bill, Trump claimed that Biden had called African Americans "super predators."
"He did a crime bill," Trump said. "1994. Where you called them super predators. African Americans. Super predators. And they've never forgotten it. They've never forgotten it."
Facts First: This is false. Biden never called African Americans "super predators."
Then-first lady Hillary Clinton used the term "super predators" in a 1996 speech in New Hampshire in support of the 1994 crime bill. Biden did warn in a 1993 speech of "predators on our streets" who were "beyond the pale" in support of the crime bill. The bill itself has come under heavy criticism in recent years for being among the policies that led to mass incarceration, disproportionately affecting Black men.
But Biden himself rejected the theory of "super predators."
In a 1997 hearing arguing that most youth in the justice system weren't violent, Biden said most youth weren't "super predators."
"In 1994, there were about 1.5 million juvenile delinquency cases," Biden said then. "Less than 10% of those cases involved violent crimes. So when we talk about the juvenile justice system, we have to remember that most of the youth involved in the system are not the so-called 'super predators.' "
-- Andrew Kaczynski
This story is being updated with additional fact checks.